Professor Bing-Xing Pan’s Team Published Invited Review on Biological Psychiatry

Recently, the invited review titled “Amygdala circuit substrates for stress adaptation and adversity” written by Professor Bing-Xing Pan’s team from Institute of Life Science of NCU was published online in Biological Psychiatry, an international famous academic journal.

The appropriate responses to various kinds of stressful events in the living and working environment is the fundamental premise to maintain body health, while the abnormal response or excessive stress exposure is closely related to the attack of a series of somatopsychic diseases especially mental diseases. Amygdale is the core brain area for the brain to express and regulate feelings/emotion, and plays an important role in body stress response. At the invitation of Doctor John Krystal, the Editor-in-chief of Biological Psychiatry and the Head of Department of Psychiatry of Yale University, Professor Bing-Xing Pan systematically illustrates in the summary the basic composition of the neural circuits in the amygdala region of the brain and its role in stress response, the regulation of environmental and genetic factors for amygdala circuit, the structure of amygdala circuit in chronic stress and function remodeling, as well as the role of the malfunction of amygdala circuit in the occurrence of the stress-related mental diseases, and etc., and discusses the key scientific problems in the development of this field, and looks into the future development direction of the field.

This work was funded by key project of National Natural Science Foundation of China, surface project, Jiangxi Provincial Natural Science Foundation, and etc. Doctors Wen-Hua Zhang and Jun-Yu Zhang from Institute of Life Science were responsible for the information collection and summary, Doctor Andrew Holmes from National Institutes of Health provided constructive suggestion for the final draft of the paper, and Professor Bing-Xing Pan was responsible for the overall paper writing and revising, and is the independent corresponding author of the paper. Founded for over 50 years, Biological Psychiatry is hosted by American Academy of Biological Psychiatry and is a reputable famous academic journal in the field of psychiatric science.

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